Volume 21, No 3, 2014, P. 25-40
UDC 519.7
A. A. Evdokimov, S. E. Kochemazov, I. V. Otpushennikov and A. A. Semenov
Analysis of discrete automaton models of gene networks with irregular structure using symbolic algorithms
Abstract:
We introduce and analyze discrete-automaton models of gene networks where weight functions of vertices take into account various forms of regulatory activity of agents. Within the model, we analyze a discrete mapping specified by a fragment of the gene network of E.coli. For this mapping, we found a number of fixed points using SAT-approach. Also we analyze mappings specified by random graphs generated according to Gilbert–Erdos–Renyi and Watts–Strogatz models. For these mappings, it was possible to find fixed points and cycles of length 2 and 3. This work can be considered as a review of our recent results regarding discrete models of gene networks and symbolic methods of analysis of their functioning.
Ill. 6, tab. 2, bibliogr. 27.
Keywords: discrete function, discrete automaton model of gene networks, SAT.
Evdokimov Alexander Andreevich 1
Kochemazov Stepan Evgenievich 2
Otpushennikov Ilya Vladimirovich 2
Semenov Alexander Anatolievich 2
1. S. L. Sobolev Institute of Mathematics, SB RAS,
4 Acad. Koptyug Ave., 630090 Novosibirsk, Russia
2. Institute for System Dynamics and Control Theory, SB RAS,
134 Lermontov St., 664033 Irkutsk, Russia
e-mail: evdok@math.nsc.ru, veinamond@gmail.com, otilya@yandex.ru, biclop.rambler@yandex.ru
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